While IUI after failed IVF is not the usual approach, some hopeful parents consider it due to cost, having never tried IUI or wanting to give it another shot.
Before deciding on IUI, understanding success rates, your medical history and alternative options could help you make an informed decision that saves time, money and emotional strain.
Below, we’ll explore the success rates of IUI and IVF and discuss alternative family-building options like surrogacy.
If you’d like personalized guidance, our fertility specialists are here to help.
Not sure if you want to try another IVF cycle? Check out our easy-to-follow guide to when it may be time to consider other options.
Can IUI Work After Failed IVF?
IUI after failed IVF is typically not recommended because success rates for IUI are generally lower than those of IVF.
IVF is usually recommended after less invasive options like IUI fail or if there are fertility issues that IUI cannot overcome. This is because IUI is less controlled than IVF and relies on natural fertilization after sperm is injected into the uterus, whereas IVF involves fertilization in a lab, allowing for better embryo selection before implantation.
However, some intended parents consider IUI after failed IVF due to cost, having never tried IUI before or wanting to give it another shot. If you’re wondering whether IUI is a viable next step, it’s important to understand the factors that may influence its success.
IUI Success After Failed IVF: What Do the Numbers Say?
Fertility specialists don’t usually recommend doing IUI after failed IVF because IVF has a much higher success rate. If you’ve already gone through IVF without success, it’s usually due to underlying infertility factors that may also reduce the chances of IUI working.
To understand why IUI may not be the best option, here are the success rates of different procedures:
- The ongoing pregnancy success rate of IUI after failed IVF is about 5% per cycle.
- The pregnancy success rate of IUI before IVF ranges between 10% and 20% per cycle.
- IVF success rates are significantly higher, with a 13.3% to 54% chance of a live birth per cycle, depending on factors like age and embryo quality.
Ultimately, your likelihood of IUI success after failed IVF depends on your individual medical circumstances. Some people have been able to conceive with IUI after failed IVF, but the chances are lower.
If you’re feeling discouraged, know that there are still paths to parenthood that may offer a greater chance of success. Learn more about your options after failed IVF.
When Going Back to IUI After Failed IVF May Not Be Successful
Although some parents consider IUI after failed IVF, there are several reasons why it may not be the best course of action:
- Tubal or uterine issues: If fallopian tube blockages, endometriosis or uterine issues contributed to IVF failure, IUI will not address these medical concerns.
- Age-related infertility: As maternal age increases, egg quality and ovarian reserve decrease, making IVF the more effective option compared to IUI.
- Multiple IUI failures in the past: If prior IUI cycles were unsuccessful before moving to IVF, the likelihood of IUI working after failed IVF is even lower.
Understanding these factors can help you decide if IUI is a viable next step or if alternative options may offer a higher chance of success.
When IUI After IVF May Be Worth Considering
While IUI after IVF is not typically recommended, there are a few situations where it may be considered:
- Unexplained infertility: If IVF was attempted without a clear diagnosis of infertility, and there are no known egg, sperm, or uterine issues, IUI may still be a viable option.
- Different medication protocols: If your IVF cycle used a particular stimulation protocol that didn’t work well for you, trying IUI with a different medication regimen could yield better results.
- Cost considerations: For couples who cannot afford another round of IVF, a few cycles of IUI may be a lower-cost alternative before pursuing other options.
It’s important to discuss these factors with your fertility specialist to determine whether IUI is a reasonable next step based on your medical history and fertility goals.
Alternatives to Doing IUI After Failed IVF
Going through IVF is a huge emotional and financial commitment, and after a failed cycle, it makes sense to want a more affordable option. IUI might seem like a way to cut costs, but unsuccessful cycles can add up quickly, both financially and emotionally.
If you’re feeling overwhelmed or unsure about what to do next, it may be time to explore other paths to parenthood.
Many fertility specialists recommend exploring options that offer a higher chance of success, such as:
- Donor eggs: If poor egg quality contributed to failed IVF, using donor eggs can significantly improve your chances of a successful pregnancy. You can choose an egg donor who fits your preferred characteristics, and your partner’s sperm (or donor sperm) is used to create embryos.
- Donor embryos: Some hopeful parents turn to donated embryos, which means you won’t have to go through another round of egg retrieval. This can be a more affordable option for those open to using an embryo that isn’t genetically related to them.
- Gestational surrogacy: If carrying a pregnancy is no longer an option, surrogacy allows you to have a biological child using your own embryo. With a healthy surrogate, your embryo has a better chance of implantation and a successful pregnancy.
Before diving into IUI after failed IVF, consider talking to your doctor about the factors contributing to your unsuccessful IVF cycles. Check out our guide to questions to ask your doctor after failed IVF.
Why Choose Surrogacy After Failed IVF
If you already have viable embryos from IVF, surrogacy could be your best next step. Rather than going back to IUI after failed IVF, you can begin the process of finding a surrogate who can help bring your dream of parenthood to life.
With a healthy surrogate, your chances of a successful pregnancy are significantly improved. Research shows that gestational carriers have higher rates of live births compared to IUI or traditional IVF cycles.
If failed IVF resulted from uterine issues or maternal health conditions, surrogacy bypasses these challenges by ensuring the embryo is carried by someone with a proven ability to sustain a healthy pregnancy.
At our agency, all surrogates must meet strict health requirements, including thorough medical and psychological screenings, as well as a history of at least one successful pregnancy. This helps maximize the chances of a successful surrogacy journey.
How Surrogacy Can Be Your Path Forward
Surrogacy offers more than just success where IVF may have failed. Here’s how:
- Maintaining a genetic connection: If you use your own egg and sperm, your child will still have a genetic link to you.
- Cost considerations: While surrogacy involves a greater upfront cost than IUI, it can prevent multiple failed treatments that cause more financial and emotional strain over time.
- Staying involved: Intended parents are involved throughout the surrogacy process, from selecting their surrogate to attending key milestones like ultrasounds and birth.
If you already have viable embryos from IVF, surrogacy could be your best next step. Rather than going back to IUI after failed IVF, you can begin the process of finding a surrogate who can help bring your dream of parenthood to life.
We understand how difficult it is to navigate infertility challenges, but you don’t have to do it alone. Contact one of our surrogacy specialists to explore your options and take the next step toward growing your family.