Preimplantation Genetic Testing (PGT) is often used to screen embryos for genetic abnormalities, which can aid in the selection of the healthiest embryos for transfer during an IVF cycle. PGT aims to increase the chances of a healthy pregnancy and reduce the likelihood of genetic diseases.
However, genetic testing of embryos raises ethical issues among those who are misinformed or have misconceptions about what PGT really is. We’re here to debunk any misconceptions about PGT and unpack how PGT can benefit you as your begin your family-building journey.
If you have embryos ready to go and want to explore surrogacy as a path to parenthood, contact us online now to learn about our success rates and how we can help you fast track your journey to having the family of your dreams.
The Truth About PGT
PGT is designed to improve the success rates of IVF and a healthy pregnancy. By identifying genetically normal embryos, PGT can reduce the emotional and financial stress associated with failed transfers and multiple IVF cycles and the likelihood of miscarriages.
Women over the age of 35 Those who want to selectively implant a single embryo to avoid the risk of a multiples pregnancy Those who have failed previous IVF cycles Those with a history of unexplained miscarriages Those with previous chromosomal abnormal pregnancies Couples with a single-gene disorder or sex-linked genetic disorder Couples who want to select the gender of their childCandidates for Genetic Testing on Frozen Embryos
PGT also holds significant promise for surrogate pregnancies. By ensuring the selected embryos are healthy, the chances of a successful pregnancy for surrogates is higher, benefiting both the intended parents and the surrogate.
Ethical Issues With Genetic Testing Of Embryos
Concern 1: Discarding Leftover Embryos
One argument against the genetic testing of embryos is the potential need to discard embryos that carry genetic abnormalities. Some people believe this is equivalent to destroying potential life.
Reality
PGT is often performed at the embryonic stage, which is early in development. Decisions about embryo disposition are made by the intended parents in accordance with individual and societal values.
The primary goal of PGT is to select the healthiest embryos to improve the chances of a successful pregnancy and reduce the risk of genetic disorders. This selection process can ultimately lead to fewer failed pregnancies and healthier outcomes for both the child and parents.
Many couples also have the option to donate unused embryos for research, contributing to scientific advancements that could benefit many.
Concern 2: PGT Discriminates Against Disabilities or Genetic Conditions
Another argument against the genetic testing of embryos is that it may promote discrimination against disabilities. By selecting against embryos with genetic conditions, it is suggested that society may devalue the lives of those living with these conditions.
Reality
PGT is not intended to devalue those with disabilities. Instead, PGT often prevents the transmission of serious genetic diseases, and decisions are made to protect future children from suffering.
Many couples choose to undergo PGT to avoid the emotional and financial burdens associated with lifelong care for a child with severe genetic disorders. It is also worth mentioning that PGT allows parents to make decisions based on their circumstances rather than societal judgment.
Concern 3: Handpicking Certain Characteristics or Overstepping Natural Boundaries.
Critics question the ethics of genetic screening embryos arguing that PGT might lead to "designer babies," where parents select embryos based on preferred traits, such as intelligence, physical appearance or gender.
Reality
PGT is a medical tool designed to improve chances of an embryo transfer resulting in a pregnancy and reduce the risk of genetic diseases, rather than altering the fundamental nature of reproduction.
Currently, PGT is primarily used to screen for serious genetic conditions and chromosomal abnormalities, not for selecting non-medical traits. The American Society for Reproductive Medicine (ASRM) and other ethical bodies regulate the use of PGT to ensure it is performed responsibly and ethically.
Although PGT-A may sometimes be used for gender selection, the primary use for PGT is to help parents have healthy children and avoid passing on debilitating diseases, not to create "perfect" children.
PGT vs. Genetic Modification
There is often confusion between PGT and genetic modification. Some people fear that PGT involves altering an embryo's genetic makeup, which raises significant ethical and safety concerns.
PGT is fundamentally different from genetic modification. While genetic modification involves altering an embryo's DNA, PGT simply screens embryos for existing genetic abnormalities. No genetic material is changed or manipulated during PGT. The goal is to select the healthiest embryos for transfer, which helps increase the chances of a successful pregnancy and a healthy child.
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The ethical issues with genetic testing of embryos are complex and often come from misinformation about the process. While concerns about PGT are valid, it's important to balance these with the benefits of preventing genetic diseases and improving IVF and surrogacy outcomes.
PGT can help you make the best decision for your situation and may increase the likelihood of a healthy pregnancy and child. Understanding the realities of PGT and how they can benefit you on your journey to parenthood can put you on the right track toward building the family of your dreams.
If you have embryos ready and are interested in beginning the first steps of the surrogacy process, contact us online now or call us at 1-800-875-2229.